Disciplines
Female Urogenital Diseases and Pregnancy Complications
Abstract (300 words maximum)
Introduction: The Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) is used to determine insulin resistance in individuals. During pregnancy, several variables may be related to HOMA-IR, including age, gestational weight gain (GWG), and body mass index (BMI), which classifies an individual's weight as healthy or unhealthy. The objective of this research is to test the relationships of age, GWG at 20-weeks, and BMI at 20-weeks with log HOMA-IR. Methods: Twenty-six women (27.8±4.2 years; 74.1% white) completed this study between 2015 and 2016. HOMA-IR was measured using fasting plasma insulin and blood glucose (fasting insulin[microU/L] x fasting glucose [nmol/L]/22.5). The Pearson Correlation test was used to determine correlations between the variables. Results: Mean GWG at 20-weeks was 5.3kg±5.1 (range -5.4 kg to 15.9 kg). BMI at 20-weeks ranged from 19.7 kg/m2 to 43.5 kg/m2, with an average of 29.6444 kg/m2, ±5.99733. There was a correlation between (r=0.614, p=0.001) HOMA-IR and BMI at 20-weeks. There was no correlation between HOMA-IR and age (r=0.044, p=0.83), nor between HOMA-IR and GWG at 20-weeks (r=0.173, p=0.39). Conclusion: Our study showed there was no correlation between age and HOMA-IR, nor between GWG at 20-weeks and HOMA-IR; however, a correlation between BMI at 20-weeks and HOMA-IR was found. These findings may allow practitioners to understand how HOMA-IR relates to female body fat and thus monitor this variable during pregnancy to avoid complications.
Academic department under which the project should be listed
WCHHS - Exercise Science and Sport Management
Loading...
Primary Investigator (PI) Name
Katherine Ingram
Additional Faculty
Sadaf Dabeer, Exercise Science and Sport Management, sdabeer@kennesaw.edu
Juliana Meireles, Exercise Science and Sport Management, jfilguei@kennesaw.edu
The association between Age, BMI, and Gestational Weight Gain with HOMA-IR during pregnancy
Introduction: The Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) is used to determine insulin resistance in individuals. During pregnancy, several variables may be related to HOMA-IR, including age, gestational weight gain (GWG), and body mass index (BMI), which classifies an individual's weight as healthy or unhealthy. The objective of this research is to test the relationships of age, GWG at 20-weeks, and BMI at 20-weeks with log HOMA-IR. Methods: Twenty-six women (27.8±4.2 years; 74.1% white) completed this study between 2015 and 2016. HOMA-IR was measured using fasting plasma insulin and blood glucose (fasting insulin[microU/L] x fasting glucose [nmol/L]/22.5). The Pearson Correlation test was used to determine correlations between the variables. Results: Mean GWG at 20-weeks was 5.3kg±5.1 (range -5.4 kg to 15.9 kg). BMI at 20-weeks ranged from 19.7 kg/m2 to 43.5 kg/m2, with an average of 29.6444 kg/m2, ±5.99733. There was a correlation between (r=0.614, p=0.001) HOMA-IR and BMI at 20-weeks. There was no correlation between HOMA-IR and age (r=0.044, p=0.83), nor between HOMA-IR and GWG at 20-weeks (r=0.173, p=0.39). Conclusion: Our study showed there was no correlation between age and HOMA-IR, nor between GWG at 20-weeks and HOMA-IR; however, a correlation between BMI at 20-weeks and HOMA-IR was found. These findings may allow practitioners to understand how HOMA-IR relates to female body fat and thus monitor this variable during pregnancy to avoid complications.