Speckle Contrast Optical Spectroscopy to Assess Muscle Blood Flow for Monitoring Muscle Health in Older Adults
Disciplines
Bioimaging and Biomedical Optics
Abstract (300 words maximum)
Age-related reduction in muscle function and loss is present in up to 20% of adults over 65 years. In medical terminology, this condition is termed Sarcopenia. This loss of function significantly reduces mobility, and increases the risk of fractures in older individuals. Since the energy for skeletal muscle function mostly comes from oxidative metabolism. Adequate oxygen delivery to muscles is critical to meeting the metabolic demand during daily activities and exercise. Thus, continuous measurement of the oxygen level and blood flow in muscles provides important information on muscle health and function. Speckled Contrast Optical Spectroscopy (SCOS) is an optical based technique that measures speckled contrast with point sources at varying distances and detects photons that undergo several scattering. The SCOS system will consist of a lens, fiber-optic probe, charged-couple device (CCD) camera, and a near-infrared laser.
The information provided by this technique is used to measure changes in blood flow. The project goal is to utilize a focusing lens within a SCOS system to assess speckle contrast and evaluate differences in data quality with and without the focusing lens. Through refining the SCOS technique, we aim to gain more accurate muscle blood flow information when assessing muscle health in older adults.
Academic department under which the project should be listed
SPCEET - Electrical and Computer Engineering
Primary Investigator (PI) Name
Paul Lee
Speckle Contrast Optical Spectroscopy to Assess Muscle Blood Flow for Monitoring Muscle Health in Older Adults
Age-related reduction in muscle function and loss is present in up to 20% of adults over 65 years. In medical terminology, this condition is termed Sarcopenia. This loss of function significantly reduces mobility, and increases the risk of fractures in older individuals. Since the energy for skeletal muscle function mostly comes from oxidative metabolism. Adequate oxygen delivery to muscles is critical to meeting the metabolic demand during daily activities and exercise. Thus, continuous measurement of the oxygen level and blood flow in muscles provides important information on muscle health and function. Speckled Contrast Optical Spectroscopy (SCOS) is an optical based technique that measures speckled contrast with point sources at varying distances and detects photons that undergo several scattering. The SCOS system will consist of a lens, fiber-optic probe, charged-couple device (CCD) camera, and a near-infrared laser.
The information provided by this technique is used to measure changes in blood flow. The project goal is to utilize a focusing lens within a SCOS system to assess speckle contrast and evaluate differences in data quality with and without the focusing lens. Through refining the SCOS technique, we aim to gain more accurate muscle blood flow information when assessing muscle health in older adults.