Hypberbaric oxygen therapy and skin substitution on the healing of chronic wounds
Abstract (300 words maximum)
Abstract
In persons living with diabetes mellitus are associated poor health outcomes including immobility, infections, and amputations. The literature is complete with published findings on the use of hyperbaric oxygen therapy and synthetic skin substitution in promoting wound healing. However, there is limited published evidence comparing the effectiveness of the two therapies. Using the PRISMA statement guidelines, we searched the Nursing & Allied Health Database using the keywords chronic wound healing, hyperbaric oxygen therapy, and skin substitution to retrieve relevant studies. Among the literature retrieved, 22 articles were included in this review because they met the predetermined inclusion criteria. The criteria were that the research had no affiliations between therapy received by the participants and the authors or any form of sponsorship by a product affiliated organization. The review yielded mixed results. Few studies reported the effectiveness of hyperbaric oxygen therapy compared to skin substitution therapy in treating chronic wounds with some indicating the therapies be co-indicated and other indicating no significant difference between the two therapies. There is insufficient evidence based on the literature examined to use one therapy over the other to reduce adverse health events. More random control trials are needed to determine the direct clinical outcomes of patients with co-indicated chronic wounds receiving these two treatments.
Keywords: hyperbaric oxygen therapy, skin substitute, chronic wounds
Hypberbaric oxygen therapy and skin substitution on the healing of chronic wounds
Abstract
In persons living with diabetes mellitus are associated poor health outcomes including immobility, infections, and amputations. The literature is complete with published findings on the use of hyperbaric oxygen therapy and synthetic skin substitution in promoting wound healing. However, there is limited published evidence comparing the effectiveness of the two therapies. Using the PRISMA statement guidelines, we searched the Nursing & Allied Health Database using the keywords chronic wound healing, hyperbaric oxygen therapy, and skin substitution to retrieve relevant studies. Among the literature retrieved, 22 articles were included in this review because they met the predetermined inclusion criteria. The criteria were that the research had no affiliations between therapy received by the participants and the authors or any form of sponsorship by a product affiliated organization. The review yielded mixed results. Few studies reported the effectiveness of hyperbaric oxygen therapy compared to skin substitution therapy in treating chronic wounds with some indicating the therapies be co-indicated and other indicating no significant difference between the two therapies. There is insufficient evidence based on the literature examined to use one therapy over the other to reduce adverse health events. More random control trials are needed to determine the direct clinical outcomes of patients with co-indicated chronic wounds receiving these two treatments.
Keywords: hyperbaric oxygen therapy, skin substitute, chronic wounds