The storage and retrieval of information are important functions of information systems (IS). These IS functions have been realized for decades, due to the maturity of the relational database technology. In recent years, the concept of Semantic Information System (SIS) has emerged as IS in which information is represented with explicit semantic based on its meaning rather than its syntax to enable its automatic and intelligent processing by computers. At present, there is a shortage of discussions on the topic of semantic data storage in IS as compared to the relational database storage counterpart. This study uses a combination of qualitative and quantitative methods to discuss semantic data storage in IS. The qualitative method is by means of literature review to learn the existing techniques for representing and storing semantic data. The quantitative method is done with experiments to empirically discuss these techniques. The empirical findings of the study shed light on the technologies and approaches utilised to store semantic data in relational databases. This may contribute to the understanding of semantic technologies in IS and foster the development of semantic information systems.