Effects of Nontraditional Exercise Interventions on the Cardiovascular System
Primary Investigator (PI) Name
Daphney Carter
Department
WCHHS - Exercise Science and Sport Management
Abstract
Patients on bedrest or with casts face issues with loss of muscle mass, however, a 5-min blood flow restriction (BFR) protocol may mitigate these changes. BFR can be painful and uncomfortable, thus our purpose is to see if a 3-minute BFR protocol is a preferable alternative. Methods: This is an ongoing study. Using a within-subject design, participants complete 4 visits with familiarization on visit 1. On visits 2-4, participants have one of three conditions with either cuff inflation on the dominant arm for 0-min (CON), 3-min (BFR3), or 5-min (BFR5) cycles. Following a 5-min rest with the dominant arm abducted 90 degrees measures of pain, discomfort, and tissue saturation index were recorded. The BFR pressure is determined as 80% of the minimum pressure necessary to stop blood flow. In the 30 seconds of cuff inflation, participants rate pain and discomfort with separate 10-point scales. The slope of tissue saturation index (measured via near infrared spectroscopy) following 15 sec after cuff deflation was recorded as a measure of microvascular function. For statistical analysis, we plan to calculate three change scores (first cycle-baseline; fifth cycle-baseline; last cycle-baseline) and compare these using a two-way Bayesian Repeated Measures ANOVA. Results: Currently, one male (age: 19yrs, weight: 77.8kg, height: 176.5cm) has completed this study. His change in discomfort (A.U.) was lower for BFR3 (Last cycle: 1) and CON (Last cycle: 0) when compared to BFR5 (Last cycle: 2). His change in pain (A.U.) was the same for BFR3 and BFR5 (Last cycle: 1) while CON had no pain. Microvascular function (%/s) appears highest in response to BFR3 (Last cycle: 0.83) when compared to BFR5 (Last cycle: -0.20) and CON (Last cycle: 0.00). Conclusions: Based on preliminary findings, shorter inflations for additional cycles may be preferable in effectiveness and with less discomfort.
Disciplines
Exercise Science | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Other Kinesiology | Other Rehabilitation and Therapy
Effects of Nontraditional Exercise Interventions on the Cardiovascular System
Patients on bedrest or with casts face issues with loss of muscle mass, however, a 5-min blood flow restriction (BFR) protocol may mitigate these changes. BFR can be painful and uncomfortable, thus our purpose is to see if a 3-minute BFR protocol is a preferable alternative. Methods: This is an ongoing study. Using a within-subject design, participants complete 4 visits with familiarization on visit 1. On visits 2-4, participants have one of three conditions with either cuff inflation on the dominant arm for 0-min (CON), 3-min (BFR3), or 5-min (BFR5) cycles. Following a 5-min rest with the dominant arm abducted 90 degrees measures of pain, discomfort, and tissue saturation index were recorded. The BFR pressure is determined as 80% of the minimum pressure necessary to stop blood flow. In the 30 seconds of cuff inflation, participants rate pain and discomfort with separate 10-point scales. The slope of tissue saturation index (measured via near infrared spectroscopy) following 15 sec after cuff deflation was recorded as a measure of microvascular function. For statistical analysis, we plan to calculate three change scores (first cycle-baseline; fifth cycle-baseline; last cycle-baseline) and compare these using a two-way Bayesian Repeated Measures ANOVA. Results: Currently, one male (age: 19yrs, weight: 77.8kg, height: 176.5cm) has completed this study. His change in discomfort (A.U.) was lower for BFR3 (Last cycle: 1) and CON (Last cycle: 0) when compared to BFR5 (Last cycle: 2). His change in pain (A.U.) was the same for BFR3 and BFR5 (Last cycle: 1) while CON had no pain. Microvascular function (%/s) appears highest in response to BFR3 (Last cycle: 0.83) when compared to BFR5 (Last cycle: -0.20) and CON (Last cycle: 0.00). Conclusions: Based on preliminary findings, shorter inflations for additional cycles may be preferable in effectiveness and with less discomfort.