A Non-Invasive Diagnostic Tool : Using Near-infrared Spectroscopy to Assess Microvascular Oxygen Metabolism in Muscles of Older Adults

Disciplines

Bioimaging and Biomedical Optics

Abstract (300 words maximum)

A Non-Invasive Diagnostic Tool : Using Near-infrared Spectroscopy to Assess Microvascular Oxygen Metabolism in Muscles of Older Adults

Saba Mabood, Jaden Causey and Paul Lee

The natural aging process can cause progressive loss of muscle mass and strength in up to 20% of adults over the age of 65 . This condition is otherwise known as sarcopenia in the field of medicine. Sarcopenia leads to significant loss of mobility in older adults. The energy for skeletal muscle function primarily comes from oxidative metabolism. Adequate oxygen delivery to muscles is crucial to meeting the metabolic demand during day to day activities. Fortunately, we can gain meaningful insights on muscle health and function via regular measurement of the oxygen level. The project goal is to develop a light-based wearable sensor, utilizing NIRS technology, that can non-invasively and continuously assess the muscle health in older adults. An open source wearable NIRS cerebral health tracker - FlexNIRS - was utilized for this purpose and the results of test runs were verified. The eventual goal was to design a wearable sensor that will consist of miniaturized LEDs and photodetectors, analog circuits and microcontroller, and a bluetooth module for wireless communication. The compact form factor of the sensor will allow for attachment on forearm muscle or thigh for data collection during activity.

Academic department under which the project should be listed

SPCEET - Electrical and Computer Engineering

Primary Investigator (PI) Name

Paul Lee

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A Non-Invasive Diagnostic Tool : Using Near-infrared Spectroscopy to Assess Microvascular Oxygen Metabolism in Muscles of Older Adults

A Non-Invasive Diagnostic Tool : Using Near-infrared Spectroscopy to Assess Microvascular Oxygen Metabolism in Muscles of Older Adults

Saba Mabood, Jaden Causey and Paul Lee

The natural aging process can cause progressive loss of muscle mass and strength in up to 20% of adults over the age of 65 . This condition is otherwise known as sarcopenia in the field of medicine. Sarcopenia leads to significant loss of mobility in older adults. The energy for skeletal muscle function primarily comes from oxidative metabolism. Adequate oxygen delivery to muscles is crucial to meeting the metabolic demand during day to day activities. Fortunately, we can gain meaningful insights on muscle health and function via regular measurement of the oxygen level. The project goal is to develop a light-based wearable sensor, utilizing NIRS technology, that can non-invasively and continuously assess the muscle health in older adults. An open source wearable NIRS cerebral health tracker - FlexNIRS - was utilized for this purpose and the results of test runs were verified. The eventual goal was to design a wearable sensor that will consist of miniaturized LEDs and photodetectors, analog circuits and microcontroller, and a bluetooth module for wireless communication. The compact form factor of the sensor will allow for attachment on forearm muscle or thigh for data collection during activity.