Synthesis and Characterization of a Series of Diphenyldipyrazolylmethane Complexes with Zinc(II)

Department

Chemistry and Biochemistry

Document Type

Article

Publication Date

5-15-2009

Abstract

The zinc(II) coordination chemistry of a series of diphenyldipyrazolylmethane ligands was explored using 1H NMR and single crystal X-ray diffraction. Unsubstituted diphenyldipyrazolylmethane (dpdpm), diphenylbis(3-methylpyrazolyl)methane (dpdp′m), and diphenylbis(3,5-dimethylpyrazolyl)methane (dpdp″m) were reacted with Zn(NO3)2 to afford Zn(dpdpm)(NO3)2, Zn(dpdp′m)(NO3)2 and Zn(Pz″)2(NO3)2 where Pz″ = 3,5-dimethylpyrazole, respectively. All attempts to isolate Zn(dpdp″m)(NO3)2 with the intact dpdp″m ligand were unsuccessful due to decomposition of the ligand. These bidentate ligands support the formation of 1:1 ligand to metal complexes and structurally model the two histidine coordination mode common in zinc proteins.

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