Document Type
Event
Start Date
23-4-2023 5:00 PM
Description
The objective of this comparative analysis is to study the behavior of the Original, alpha, beta, gamma, delta, and omicron variants of SARS-CoV-2 coronavirus under conditions that resemble the human body. To achieve this, we conducted Molecular Dynamics simulations for all variants in the same environment. Additionally, we conducted salt bridge and hydrogen bond analyses to further investigate the behavior of the SARS-CoV-2 variants. These analyses allowed us to examine the interactions between amino acid residues and to determine the stability of the protein structures. By integrating these analyses with our Molecular Dynamics simulations, we were able to gain a comprehensive understanding of the behavior of each variant in a human-like environment. This information could be crucial in developing effective treatments and vaccines against COVID-19. Overall, our study provides valuable insights into the molecular dynamics and protein-protein interactions of the SARS-CoV-2 variants and highlights the importance of further research in this area to combat the ongoing pandemic.
GR-389 Molecular Dynamics and Protein-Protein Interactions (PPIs) on SARS-CoV-2 coronavirus
The objective of this comparative analysis is to study the behavior of the Original, alpha, beta, gamma, delta, and omicron variants of SARS-CoV-2 coronavirus under conditions that resemble the human body. To achieve this, we conducted Molecular Dynamics simulations for all variants in the same environment. Additionally, we conducted salt bridge and hydrogen bond analyses to further investigate the behavior of the SARS-CoV-2 variants. These analyses allowed us to examine the interactions between amino acid residues and to determine the stability of the protein structures. By integrating these analyses with our Molecular Dynamics simulations, we were able to gain a comprehensive understanding of the behavior of each variant in a human-like environment. This information could be crucial in developing effective treatments and vaccines against COVID-19. Overall, our study provides valuable insights into the molecular dynamics and protein-protein interactions of the SARS-CoV-2 variants and highlights the importance of further research in this area to combat the ongoing pandemic.