Analysis of Nanoceria Using Raman Spectroscopy
Disciplines
Biological and Chemical Physics | Physics
Abstract (300 words maximum)
Nanoceria, the simplified name for cerium oxide nanoparticles, has been found to have significant antioxidant properties that allow for clinical uses in combating neurodegenerative diseases. The coexistence of the two valence states, Ce3+ and Ce4+, within the nanoceria provides its antibacterial and anti-cancerous properties. To investigate the existence of the Ce3+ and Ce4+ valence states, two sets of bio-glasses, NaBCe4 and NaBCe6, were melted at the high-temperature furnace for 3 hours at 1100°C. The melt is quenched, and the glass samples were heat-treated for 10 minutes, 20 minutes, 30 minutes, and 1 hour at 500°C to grow the crystals. Using a mortar and pestle, the glass pieces were crushed and sifted into particles less than 500 microns but greater than 425 microns. These samples were then investigated under Raman spectroscopy using a 532-nanometer laser to analyze the chemical structure of the bio-glass samples. Results showed that the NaBCe4 samples had peaks at 502cm-1 and 580cm-1, signifying that there were nanoceria of Ce3+ valence inside the samples. Inside the NaBCe6 samples, peaks at 440cm-1 were sighted, meaning there were significant amounts of nanoceria of Ce4+ valence in the samples. These results indicate nanoceria with Ce4+ in NaBCe4 tends to transform into Ce3+ valence as the glass is heat treated, whilst the nanoceria in NaBCe6 transforms to Ce4+ as the glass is heat treated for 30 minutes.
Academic department under which the project should be listed
CSM - Physics
Primary Investigator (PI) Name
Kisa Ranasinghe
Analysis of Nanoceria Using Raman Spectroscopy
Nanoceria, the simplified name for cerium oxide nanoparticles, has been found to have significant antioxidant properties that allow for clinical uses in combating neurodegenerative diseases. The coexistence of the two valence states, Ce3+ and Ce4+, within the nanoceria provides its antibacterial and anti-cancerous properties. To investigate the existence of the Ce3+ and Ce4+ valence states, two sets of bio-glasses, NaBCe4 and NaBCe6, were melted at the high-temperature furnace for 3 hours at 1100°C. The melt is quenched, and the glass samples were heat-treated for 10 minutes, 20 minutes, 30 minutes, and 1 hour at 500°C to grow the crystals. Using a mortar and pestle, the glass pieces were crushed and sifted into particles less than 500 microns but greater than 425 microns. These samples were then investigated under Raman spectroscopy using a 532-nanometer laser to analyze the chemical structure of the bio-glass samples. Results showed that the NaBCe4 samples had peaks at 502cm-1 and 580cm-1, signifying that there were nanoceria of Ce3+ valence inside the samples. Inside the NaBCe6 samples, peaks at 440cm-1 were sighted, meaning there were significant amounts of nanoceria of Ce4+ valence in the samples. These results indicate nanoceria with Ce4+ in NaBCe4 tends to transform into Ce3+ valence as the glass is heat treated, whilst the nanoceria in NaBCe6 transforms to Ce4+ as the glass is heat treated for 30 minutes.