Towards the synthesis and characterization of a new trisNHC ligand
Disciplines
Biochemistry | Organic Chemistry
Abstract (300 words maximum)
The chemical industry heavily relies on transition metal catalysts to efficiently create a variety of petrochemicals. Catalysis allows these changes to happen under mild conditions, all while ensuring high selectivity and yield. This makes it essential to develop new catalyst systems that boost activity using cost-effective materials in mild conditions. Over the past several decades, N-heterocyclic carbenes (NHCs) have surfaced as a significant class of carbon-based ligands. Their unique electronic and steric properties have made them valuable components in many catalytically active metal complexes. A key factor in the advancement of NHC-based catalysis has been the design and synthesis of new NHCs, which offer a variety of electronic and steric characteristics. This project is centered around creating a novel, rigid, anionic polyNHC. This distinctive carbene could act as a foundation for developing a range of trimetallic complexes and metallo-supramolecular systems—innovative structures that existing NHC ligands can’t achieve. Thanks to their unique electronic properties, these NHC-metal complexes are expected to offer significant benefits over traditional cationic metal complexes of neutral NHCs, including improved reactivity and solubility. Moreover, we'll be sharing our progress in integrating this ligand into a series of transition metal complexes.
Academic department under which the project should be listed
CSM - Chemistry and Biochemistry
Primary Investigator (PI) Name
Daniela Tapu
Towards the synthesis and characterization of a new trisNHC ligand
The chemical industry heavily relies on transition metal catalysts to efficiently create a variety of petrochemicals. Catalysis allows these changes to happen under mild conditions, all while ensuring high selectivity and yield. This makes it essential to develop new catalyst systems that boost activity using cost-effective materials in mild conditions. Over the past several decades, N-heterocyclic carbenes (NHCs) have surfaced as a significant class of carbon-based ligands. Their unique electronic and steric properties have made them valuable components in many catalytically active metal complexes. A key factor in the advancement of NHC-based catalysis has been the design and synthesis of new NHCs, which offer a variety of electronic and steric characteristics. This project is centered around creating a novel, rigid, anionic polyNHC. This distinctive carbene could act as a foundation for developing a range of trimetallic complexes and metallo-supramolecular systems—innovative structures that existing NHC ligands can’t achieve. Thanks to their unique electronic properties, these NHC-metal complexes are expected to offer significant benefits over traditional cationic metal complexes of neutral NHCs, including improved reactivity and solubility. Moreover, we'll be sharing our progress in integrating this ligand into a series of transition metal complexes.