Effect of pseudomonas lipase enzyme on the degradation of polycaprolactone/polycaprolactone-polyglycolide fiber blended nanocomposites
Department
Systems and Industrial Engineering
Document Type
Article
Publication Date
3-16-2018
Abstract
This study describes the interaction resulting from adding pseudomonas lipase (PS) enzyme to polycaprolactone-based composites designed for orthopedic applications. The biopolymer composite evaluated in this study consists of electrospun polycaprolactone (PCL)/polyglycolide (PGA) blended fibers impregnated with double stranded deoxyribonucleic acid wrapped single-walled carbon nanotubes encapsulated by a PCL matrix. PS enzyme was used to catalyze the degradation of PCL-based biocomposites. PCL present in the biocomposites showed considerable degradation in 4 weeks in the presence of the enzyme, exhibiting a contrast to hydrolytic degradation which lasts several years. PGA-consisting fibers degraded completely within one week of exposure to the enzyme.
Journal Title
International Journal of Polymeric Materials and Polymeric Biomaterials
Journal ISSN
0091-4037
Volume
68
Issue
7
First Page
360
Last Page
367
Digital Object Identifier (DOI)
10.1080/00914037.2018.1445633