Title

Effect of pseudomonas lipase enzyme on the degradation of polycaprolactone/polycaprolactone-polyglycolide fiber blended nanocomposites

Department

Systems and Industrial Engineering

Document Type

Article

Publication Date

3-16-2018

Abstract

This study describes the interaction resulting from adding pseudomonas lipase (PS) enzyme to polycaprolactone-based composites designed for orthopedic applications. The biopolymer composite evaluated in this study consists of electrospun polycaprolactone (PCL)/polyglycolide (PGA) blended fibers impregnated with double stranded deoxyribonucleic acid wrapped single-walled carbon nanotubes encapsulated by a PCL matrix. PS enzyme was used to catalyze the degradation of PCL-based biocomposites. PCL present in the biocomposites showed considerable degradation in 4 weeks in the presence of the enzyme, exhibiting a contrast to hydrolytic degradation which lasts several years. PGA-consisting fibers degraded completely within one week of exposure to the enzyme.

Journal

International Journal of Polymeric Materials and Polymeric Biomaterials

Journal ISSN

0091-4037

Volume

68

Issue

7

First Page

360

Last Page

367

Digital Object Identifier (DOI)

10.1080/00914037.2018.1445633

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