Concerns with the Methodology, Analysis, and Discussion of the Buzzy® and Transillumination Comparison Article
Statistics and Analytical Sciences
In the article by Dr. Lima-Oliveira et al., "A new device to relieve venipuncture pain can affect haematology test results"1, prolonged application of a Buzzy®/ice pack unit with the elastic tourniquet included resulted in different laboratory values from those in free-flowing blood collected with transillumination. As the physician inventor and manufacturer of the Buzzy® device, I appreciate the opportunity to respond to the findings, clarify appropriate use of our product, and illuminate a source of bias not considered in the discussion. As laboratory analysis and procedures are an integral part of the discussion, a statistician familiar with comparative sample methodology has reviewed the work as well.
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